Webinar: Non-targeted Screening for Environmental Water Quality Monitoring

The ever-increasing production and use of chemicals augment their occurrence in drinking water and its sources to an extent that monitoring, using targeted chemical analyses alone, is no longer sufficient. Complementary methods that can detect a multitude of chemicals simultaneously, referred to as suspect and non-target screening, are required, and must also be able to detect mobile and polar compounds in low concentrations.

These methods rely on liquid chromatography coupled to high resolution mass spectrometry in combination with novel data analysis workflows. The range of challenges in their application and strategies to overcome these will be presented, such as the identification of “known unknowns” and “unknown unknowns” in different water matrices and the confidence thereof, the automation of non-target screening data analysis, and the use of cheminformatics and data mining for the prioritization of suspect chemicals.

Key Learning Objectives

Understand the challenges of ensuring water quality
How to confidently identify “known unknown” and “unknown unknown” emerging contaminants
Automation and streamlining of complex data analysis