{"id":76709,"date":"2024-10-03T09:21:18","date_gmt":"2024-10-03T07:21:18","guid":{"rendered":"https:\/\/www.kwrwater.nl\/?p=76709"},"modified":"2024-10-03T09:21:18","modified_gmt":"2024-10-03T07:21:18","slug":"persistent-and-mobile-kwr-joins-zeropms-workshop-in-dessau-germany","status":"publish","type":"post","link":"https:\/\/www.kwrwater.nl\/en\/actueel\/persistent-and-mobile-kwr-joins-zeropms-workshop-in-dessau-germany\/","title":{"rendered":"Persistent and mobile \u2013 KWR joins ZeroPM\u2019s workshop in Dessau, Germany"},"content":{"rendered":"<div class=\"post_intro\">\n<p>KWR participated in the ZeroPM consortium&#8217;s 2<sup>nd<\/sup> workshop on September 19-20, 2024, in Dessau-Ro\u00dflau, Germany. The event was held at the German Environment Agency (UBA), focused on minimizing pollution from persistent and mobile substances (PM), by bringing together 140 experts from academia, government, industry, NGOs, and the water sector. Discussions centered on tackling so-called &#8220;forever chemicals&#8221;, hazard classification, prioritization methods, and risk assessment. Researchers highlight that models can only be as good as the quality of input data, and regulators remind the research needs for regulating hazardous chemicals. The workshop reinforced KWR&#8217;s commitment to bridging science and practice for better water quality.<\/p>\n<\/div>\n<h2>ZeroPM\u2019s Mission and Workshop Objectives<\/h2>\n<p>On the 19<sup>th<\/sup> and 20<sup>th<\/sup> of September 2024, KWR travelled to Dessau-Ro\u00dflau, Germany, to participate in the 2<sup>nd<\/sup> workshop of the <a href=\"https:\/\/zeropm.eu\/who-is-zeropm\/\" target=\"_blank\" rel=\"noopener\">ZeroPM<\/a> consortium, hosted by the German Federal Environment Agency (UBA). This EU project is one of the most active initiatives aimed at establishing an evidence-based multilevel framework to minimize the use, emissions, and pollution from persistent and mobile substances, thereby protecting European water resources and mitigating risks to human health.<\/p>\n<p>This workshop, titled \u201cAchieving Zero Pollution of Persistent and Mobile Substances:\u202fPrioritization through Substance Grouping and Risk Assessment,\u201d gathered around 140 participants from academia, government, industry, NGOs, regulatory bodies, and the water sector. The Chemical Water Quality and Health team accepted the open call from the consortium, recognizing the relevance of the drinking water sector\u2019s presence. The content and organization of the event were of high quality, providing an opportunity to expand and strengthen relationships among experts and other stakeholders in <a href=\"https:\/\/www.kwrwater.nl\/en\/onderzoek\/health-en\/emerging-contaminants\/\" target=\"_blank\" rel=\"noopener\">fields<\/a> where KWR is actively involved. The discussions in the lively Discussion Caf\u00e9s allowed participants to learn, share insights, raise doubts and explore ways to move towards a future with zero water pollution.<\/p>\n<p>A significant focus was placed on &#8220;forever chemicals,&#8221; which are resistant to degradation in the environment (persistent, P) and easily move between matrices (mobile, M), particularly in water, and across large distances (Figure 1). PM substances are now ubiquitous in water, air, soil, and living organisms worldwide. They are very difficult to remove once in the environment and can contaminate our drinking water sources. Without effective actions on removal, prioritization and prevention, their presence and that of other concerning contaminants is expected to only increase.<\/p>\n<p>&nbsp;<\/p>\n<div class=\"wp-caption alignnone\" style=\"width: 616px\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.kwrwater.nl\/wp-content\/uploads\/2024\/10\/Picture-CLP-criteria-780x470.jpg\" alt=\"\" width=\"616\" height=\"371\" \/><p class=\"wp-caption-text\">Figure 1. EU CLP criteria for PMT\/vPvM substances. Source: Chirsir et al. (2024)<\/p><\/div>\n<p>The workshop addressed topics directly related to <a href=\"https:\/\/www.kwrwater.nl\/en\/research-agenda\/\" target=\"_blank\" rel=\"noopener\">ongoing and upcoming research activities<\/a> at KWR, including screening approaches for persistence and mobility, transformation products, substance grouping, exposure assessment, NAM-based hazard characterization, in vitro-in vivo extrapolation, risk assessment, reducing data gaps, quantifying uncertainties, and multi-stakeholder approaches towards zero pollution.<\/p>\n<h2>Research Needs and Limitations in Identifying Hazardous Substances<\/h2>\n<p>The event began with essential perspectives from regulatory bodies, including ECHA and UBA, discussing the research needs and limitations in identifying and prioritizing hazardous substances. Daunting figures were presented by some presenters, for example, highlighting the small number of substances currently regulated worldwide compared to the vast number of potentially very persistent and mobile (vPvM) substances and their transformation products.<\/p>\n<p>The event also offered up-to-date knowledge on prioritizing PMT substances through grouping strategies and risk matrices. Grouping strategies are increasingly seen as a pragmatic alternative for singly assessing the hazardousness of substances by shared features, i.e., assess substances in bulk using proxy criteria rather than empirically testing each individual substance.<\/p>\n<p>For example, substances can be grouped based on structural similarity or retained moieties from transformation products. In the first approach, we can assume that structurally similar substances will likely share similar properties of concern. Consequently, a large group of substances may be regulated and managed similarly. An example is the <a href=\"https:\/\/echa.europa.eu\/nl\/-\/echa-publishes-pfas-restriction-proposal\" target=\"_blank\" rel=\"noopener\">recent proposal<\/a> to restrict thousands of PFAS in the EU, despite limited information on many of them; the few for which we have hazard and risk information are confidently viewed as concerning.<\/p>\n<p>Another approach to address knowledge gaps involved a large ontological study analysing the co-occurrence of keywords (such as PFAS and toxicity) in scientific publications to signal potential toxicological and hazardous associations.<\/p>\n<h2>Toxicity and Risk-Based Approaches for Persistent, Mobile, and Toxic Substances<\/h2>\n<p>In the second day of the conference, the focus shifted to the toxicity of classes of substances that are not only recalcitrant to degradation and easily transported, but also potentially harmful to humans and the environment (persistent, mobile and toxic; PMT) (Figure 1). The latest developments in conceptualizing a prioritization scheme based on the risk of substances were shared with attendees, and applications of multimedia activity models for evaluating the fate of persistent and mobile substances were also presented.<\/p>\n<p>Additionally, the integration of new toxicological results (e.g., endocrine-disrupting properties) of water-relevant substances using New Approach Methodologies (e.g., in vitro assays, PBK modelling) was discussed. A lively discussion followed, where stakeholders explored how to advance these approaches towards risk-based prioritization and regulatory application. Many drinking water companies struggle with substances like TFA, 1,4-dioxane, sulfamic acid, EDTA, melamine, 1H-benzotriazole, chlorothalonil M4, dikegulac and DMS. However, little is known about their emission or that of parent compounds.<\/p>\n<p>Interestingly, several attendees emphasized the critical need of publicly accessible information about waste emissions, without which even the best computer models cannot provide accurate predictions. Nonetheless, it was encouraging to witness that, despite the complex challenges of bridging science and practice, scientists and regulators across various domains (chemical, environmental, health) are increasingly willing to collaborate in finding solutions among all the data-gaps and uncertainties. \u2018Bridging science to practice\u2019 is KWR\u2019s motto, and we take pride in this role by, among its many activities, expanding the dialogue at events such as ZeroPM\u2019s workshop.<\/p>\n<p>In summary, in addition to the conceptual and practical knowledge shared among experts, this gathering provided an opportunity to stay up-to-date about the latest efforts for a future without pollution alongside key stakeholders, including academia, regulatory authorities, and industry.<\/p>\n<p>The Chemical Water Quality and Health team congratulates our colleagues at the ZeroPM for a successful gathering and looks forward to its continued success!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>KWR participated in the ZeroPM consortium\u2019s 2nd workshop on September 19-20, 2024, in Dessau-Ro\u00dflau, Germany. The event was held at the German Environment Agency (UBA), focused on minimizing pollution from persistent and mobile substances (PM), by bringing together 140 experts from academia, government, industry, NGOs, and the water sector. Discussions centered on tackling so-called \u201cforever chemicals\u201d, hazard classification, prioritization methods, and risk assessment.<\/p>\n","protected":false},"author":5,"featured_media":76711,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[631],"tags":[],"class_list":["post-76709","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Persistent and mobile \u2013 KWR joins ZeroPM\u2019s workshop in Dessau, Germany - KWR<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kwrwater.nl\/en\/actueel\/persistent-and-mobile-kwr-joins-zeropms-workshop-in-dessau-germany\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Persistent and mobile \u2013 KWR joins ZeroPM\u2019s workshop in Dessau, Germany - KWR\" \/>\n<meta property=\"og:description\" content=\"KWR participated in the ZeroPM consortium\u2019s 2nd workshop on September 19-20, 2024, in Dessau-Ro\u00dflau, Germany. 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